Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and October 2017 VOL. 14, ED 3. by PeningtonInstitute Issuu Melanotan II (Tan Jabs): Why They're Not Worth The Risk Reminder of serious health risks with 'Melanotan 2' self tan products Irish Pharmacist Avoid nasal tanning sprays or nasal tanners entirely. These products promise an all over tan without sun exposure but they are unregulated, can be unsafe, and contain potentially risky substances like Melanotan 2.