Carnitine metabolic disorders and novel clinical approaches: Mechanistic insights from deficiency management to liver and kidney disease treatment ScienceDirect Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine L carnitine helps transport fatty acids to produce energy The Importance of the Fatty Acid Transporter L Carnitine in Non Alcoholic Fatty Liver Disease (NAFLD) The Importance of the Fatty Acid Transporter L Carnitine in Non Alcoholic Fatty Liver Disease (NAFLD)